A pilot study on 25-hydroxyvitamin D status according to sun exposure in pregnant women in antwerp, Belgium
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Original Paper
VOLUME: 2 ISSUE: 2
P: 127 - 130
June 2010

A pilot study on 25-hydroxyvitamin D status according to sun exposure in pregnant women in antwerp, Belgium

Facts Views Vis ObGyn 2010;2(2):127-130
1. Department of Obstetrics and Gynaecology, Antwerp University Hospital (UZA), Wilrijkstraat 10, 2650 Edegem, Belgium.
2. Laboratory of Clincal Biology, Antwerp University Hospital (UZA), Wilrijkstraat 10, 2650 Edegem, Belgium.
3. Department of Obstetrics and Gynaecology, Antwerp University Hospital (UZA), Wilrijkstraat 10, 2650 Edegem, Belgium
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Abstract

Introduction

Vitamin D deficiency in utero or early neonatal life may have a major impact on children’s health. Little is known on vitamin D deficiency in pregnant women in Belgium, non on the impact of wearing head and/or body cover.

Objectives

This was a preliminary exploration of the vitamin D status in pregnant women visiting the antenatal clinic in the Antwerp University Hospital.

Method

From August 1 2009 until November 30 2009 we systematically determined 25-hydroxy vitamin D (25-OH vitamin D) in each blood sample taken from pregnant women visiting the antenatal clinic. We also registered the degree of head/body cover and inquired for intake of vitamin supplements.

Results

Our population consisted of 171 women, mostly primiparous, of which 86% were not covered. The mean value of 25-OH vitamin D was 28 ng/ml. Non-covered women had a mean of 29,5 ± 12,2 (SD) ng/ml, the partially covered group had a mean of 17,2 ± 7,2 (SD) ng/ml and the completely covered group had a mean of 22,5 ± 12,9 (SD) ng/ml. The difference in serum concentrations between the 3 groups was statistically significant (Anova, p < 0,00001). There were significantly more covered than non-covered women with a vitamin D concentration lower than 30 ng/ml (OR6.2; 95% CI: 1,8-21,7; p < 0,05). There was no effect of gestational age, maternal age, gravidity, parity and intake of supplements on vitamin D levels. There was a siginificant seasonal effect from summer to fall, with Vitamine D levels lowering from August to November (linear regression, p < 0,05).

Conclusion

Low vitamin D levels seem to be frequent and covered woman are at a higher risk of deficiency.  

Keywords:
Pregnancy, vitamin D, fetus, nutritional intake, antenatal care